How Chronic Inflammation Affects Mental Health and Ways to Manage It

Quick Summary

• Chronic inflammation has been connected to various mental health conditions, such as depression, anxiety, schizophrenia, and Alzheimer’s.
• Research shows elevated inflammatory markers in people with thes conditions and links chronic inflammation to disrupted brain function.
• Persistent low-grade inflammation occurs from lingering immune responses involving cytokines long after infections or injuries have resolved.
• High inflammatory activity is shown to cause disruptions in neurotransmitters like serotonin and dopamine, while oxidative stress damages neurons over time.
• Studies using genetic techniques (Mendelian randomization) suggest that specific inflammatory pathways directly cause mental illnesses.
• A leaky blood-brain barrier under chronic stress lets harmful molecules enter the brain, exacerbating neuroinflammation and neuronal damage possibly leading to Alzheimer’s plaques’ buildup.
• Researchers are investigating gut microbiota’s role – dietary patterns like the Mediterranean diet reduce systemic inflammation by supporting a healthy microbiome. Anti-inflammatory diets may also lower risks of dementia by 31%.
• Exercises reduce sedentary-inflammation risks; mindfulness reportedly offsets cortisol-driven body cycles accelerating organ damage trajectories!

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