The UK’s implementation of mitochondrial donation technology, which centers on addressing serious hereditary conditions, may have broad global implications. For India, this progress could serve as a model for integrating cutting-edge medical advancements into healthcare policy. However, adopting such measures would require thorough ethical reviews and regulatory frameworks to ensure patient safety and social acceptance in India’s diverse healthcare ecosystem. Access to such advanced treatments could reduce the burden of genetic disorders but might also intensify debates on affordability and equity.