ARRDC4-Driven Glycolysis Boosts Immunity Against Influenza A via Key Metabolite

Speedy Summary

• The Proceedings of the National Academy of Sciences published a study in its September 2025 issue (Volume 122, Issue 35) focusing on combating viral infections.
• The study highlights the importance of understanding antiviral immune mechanisms for developing effective antiviral strategies.
• Accumulating evidence underscores the meaningful role of glucose metabolism in innate immune responses to viral pathogens.

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Indian Opinion Analysis
Understanding how glucose metabolism influences innate immunity could have widespread implications for addressing major public health challenges, including viral outbreaks in India and globally. Given that India continues to battle endemic viral diseases, this research might offer insights into therapeutic innovations that leverage metabolic pathways for enhanced immunity. Promoting collaborations between Indian research institutions and global studies like these could accelerate breakthroughs tailored to India’s unique healthcare landscape.