Structural basis of the hepatitis B virus X protein in complex with DDB1

IO_AdminUncategorized18 hours ago8 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 24, June 2025.
SignificanceHBx plays a pivotal role in HBV replication by enhancing cccDNA transcription. However, the HBx structure remains unsolved, representing a significant gap in knowledge. Here, we show the cryo-EM structure of HBx in complex with DDB1…
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