Microbiome RNA Breakthrough Offers Early Colorectal Cancer Detection

Swift Summary:

• Technology Developed: Researchers introduced Low-Input Multiple Methylation Sequencing (LIME-seq), which detects RNA modifications in plasma cell-free RNA (cfRNA).
• Request: The study identified microbiome-derived RNA modification signatures capable of distinguishing people with colorectal cancer (CRC) from those without.
• Potential Impact: Monitoring cfRNA or other RNA species modifications could support disease diagnosis and prognosis.

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