Treatments for Back Pain May be Largely Ineffective
There’s some good news and bad news about treating back pain. The good news is research has identified what actually works. The bad news is, it’s not very much. Only
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Integrative spatiotemporal modeling of biomolecular processes: Application to the assembly of the nuclear pore complex
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceBiological systems are constantly in motion; therefore, describing the large-scale rearrangements of biological macromolecules is crucial to
The reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceThe interactions between the medial prefrontal cortex (mPFC) and hippocampus are crucial for memory formation and retrieval.
Diel partitioning in microbial phosphorus acquisition in the Sargasso Sea
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceIn the persistently nutrient-stressed open ocean, diverse microbes compete for scarce resources. We hypothesized that direct competition
Poverty alleviation resettlement in China reduces deforestation
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificancePoverty-driven deforestation has raised widespread concerns globally. This study deepens scientific understanding of how structured resettlement programs
Vortex reversal is a precursor of confined bacterial turbulence
Proceedings of the National Academy of Sciences, Volume 122, Issue 11, March 2025. SignificanceBiological and synthetic self-propelled entities, such as cultured cells, swimming bacteria, and active colloids, often exhibit complex
Synaptic architecture of a memory engram in the mouse hippocampus | Science
Memory engrams are formed through experience-dependent plasticity of neural circuits, but their detailed architectures remain unresolved. Using three-dimensional electron microscopy, we performed nanoscale reconstructions of the hippocampal CA3-CA1 …Read More
Unifying spatial scaling laws of biodiversity and ecosystem stability | Science
While both species richness and ecosystem stability increase with area, how these scaling patterns are linked remains unclear. Our theoretical and empirical analyses of plant and fish communities show that
Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous | Science
For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown whether asymmetric segregation
News at a glance: Flat U.S. research budget, CDC nominee dropped, and who writes review letters
The latest in science and policy…Read More
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