Quick Summary
- Growth of Blood Vessel Organoids: Researchers at Harvard University genetically engineered human stem cells to develop blood vessel organoids within five days,a significant improvement over previous methods that took weeks.
- Testing on Mice: The organoids were implanted into injured tissue in mice where blood supply was cut off. Results showed restored blood flow to 50% of normal levels and minimal tissue damage in 75% of treated animals. Non-treated mice experienced severe tissue necrosis.
- effectiveness for Diabetes Treatment: In a separate study, using these organoids alongside pancreatic tissue transplants improved blood sugar control in diabetic mice compared to pancreas-only transplants.
- Future Applications: Findings could aid medical interventions for injuries such as accidents or heart attacks, and improve lab-grown mini-organs or mini-tumors used in research and drug testing.
- Next Steps: Larger animal studies are required before human trials can commence,which researchers estimate could begin within five years.
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