Breakthrough Oral Painkiller Targets α2B Adrenoceptor

Fast Summary

• The article discusses the global health issue of pain management and its severe impact on patients’ quality of life.
• Opioids, while effective as strong painkillers, are associated with addiction risks and adverse effects when used continuously.
• This research appears in the Proceedings of the National Academy of Sciences (PNAS), Volume 122, Issue 32, August 2025.

Indian Opinion Analysis
pain management is a critical challenge in India as well as globally, since untreated or poorly managed pain considerably affects individual well-being and societal productivity. While opioids are often used as primary solutions for severe pain relief, their usage in India requires cautious approaches due to concerns over addiction rates and regulatory oversight for prescription drugs. this underscores the importance of advancing safer alternatives or novel treatments that can balance efficacy with reduced harm.

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