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Now Reading: Bruch’s membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration

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Bruch’s membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration

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Bruch’s membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration

IO_AdminUncategorized19 hours ago3 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 24, June 2025.
SignificanceLipoprotein-like particle deposition and aggregation in Bruch’s membrane is a key event in drusen biogenesis in the early and intermediate stages of age-related macular degeneration (AMD). Here, we establish that heparan sulfate, a sulfated …
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