– Eggs from both the mother and donor are fertilized via IVF.
– The nucleus (containing most DNA) is transferred from the mother’s egg to the donor’s egg while retaining donor mitochondria and other contributions.- This creates embryos containing DNA primarily from biological parents but healthy mitochondria from a separate donor.
– Out of embryos examined post-transfer into their mothers’ wombs, eight healthy babies were born (including twins).
– Blood tests showed no harmful mutations in five babies and extremely low levels in three; all are reportedly meeting developmental milestones months or years post-birth.
The triumphant use of pronuclear transfer introduces groundbreaking potential for treating hereditary illnesses worldwide. While this technique has shown promise internationally by eliminating devastating genetic conditions effectively, careful monitoring of long-term effects will remain critical.
for India-home to significant challenges affecting maternal genetics due partly cultural norms limiting testing facilities proper budget undertakes ANN technology resources mitigate efforts research human