Genetic Mutation Combo Found to Raise Blood Clot Risk by 180%

Speedy Summary

• Researchers at Lund University,Sweden,have uncovered three gene variants (ABO,F8,and VWF) tied to a 10-30% increased risk of venous blood clots in the leg.
• The risk rises as more genetic variants are present; individuals with five such variants face 180% higher likelihood of venous thrombosis.
• Venous thromboembolism affects over 10,000 people annually in Sweden and is increasing due to aging population and factors like obesity.
• Risk factors include stagnant blood flow during inactivity or travel, surgery-induced vessel wall damage, pregnancy-related coagulation changes, smoking (moderate), and obesity (significant).
• Some populations inherit genetic mutations linked to clotting disorders; for instance, APC resistance caused by Factor V Leiden mutation affects 10% of swedes but is generally prevalent among Indo-Europeans.
• Preventive methods include movement during long periods of inactivity, use of support stockings or blood thinners in high-risk scenarios like pregnancy or surgery, healthier lifestyle choices including diet and exercise changes.

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Indian Opinion analysis
While medical discoveries such as identifying new gene variants contributing to venous thrombosis might seem geographically specific to Sweden’s population dynamics for now-ageing populace combined with sedentary modern habits trends problematic those same mechanisms align proxies upto society transition-class both