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Now Reading: HCV NS3/4A protease relocalizes CCTα to viral replication sites, enhancing phosphatidylcholine synthesis and viral replication

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HCV NS3/4A protease relocalizes CCTα to viral replication sites, enhancing phosphatidylcholine synthesis and viral replication

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U.S.//Discover the latest updates from across the United States, including politics, culture, economy, and trending stories. Stay informed on the key events shaping the nation and the topics everyone’s talking about.
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HCV NS3/4A protease relocalizes CCTα to viral replication sites, enhancing phosphatidylcholine synthesis and viral replication

IO_AdminUncategorized3 months ago52 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 10, March 2025.
SignificanceLike all (+)RNA viruses, HCV modifies the cytosolic membrane of infected cells to establish RCs. Multiple (+)RNA viruses induce PC accumulation at RCs. We find that HCV infection induces de novo PC synthesis at the viral replicating site…
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