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Now Reading: LDL receptor–mediated endocytosis of Escherichia coli α-hemolysin mediates renal epithelial toxicity

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LDL receptor–mediated endocytosis of Escherichia coli α-hemolysin mediates renal epithelial toxicity

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LDL receptor–mediated endocytosis of Escherichia coli α-hemolysin mediates renal epithelial toxicity

kisded kisdedUncategorized12 hours ago5 Views

Proceedings of the National Academy of Sciences, Volume 122, Issue 24, June 2025.
SignificanceThough the α-hemolysin (HlyA) of uropathogenicEscherichia coli(UPEC) has been studied for decades, its mechanisms of action remain poorly defined. The widely held view is that it causes cytotoxicity by forming pores in the plasma membrane…
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