Single Blood Test Can Determine Age of 11 Organs and Systems
Quick Summary
- A new blood test can evaluate teh biological ages of 11 different organs and systems to detect potential health risks.
- Researchers aim to use this test to guide personalized care by determining which specific organs or systems are ageing faster.
- Customary epigenetic clocks measure overall biological age through DNA methylation but lack organ-specific precision.
- The study reviewed data from approximately 7,500 individuals and trained a model based on blood biomarkers linked to conditions in five organs (heart, lung, kidney, liver, brain) and six systems (immune, inflammatory, blood, musculoskeletal, hormone, metabolic).
- Testing on an additional dataset of 8,125 people showed the modelS scores could predict specific conditions like heart disease and cognitive decline.
- Compared with traditional methods for estimating biological age via epigenetics, this approach demonstrated comparable or improved accuracy for organ-specific aging measurements.
- Researchers stress that the test is not diagnostic but helps assess risks; further studies are needed for validation before clinical application.
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